SCHEMBL25698

SCHEMBL25698

CC(C)CC(=CC#N)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 8/20 0.38
GRIK2 Q13002 5/20 0.36
GRIA2 P42262 2/20 0.36
GRIA4 P48058 2/20 0.36
GRIK3 Q13003 2/20 0.36
GRIK5 Q16478 2/20 0.36
GRIA1 P42261 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KISS1R Q969F8 2/20 0.33
CA2 P00918 1/20 0.33
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP9 P14780 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25697 1.00 GRIK1 (0.38) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL716220 0.81 GRIK1 (0.33) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL716221 0.81 GRIK1 (0.33) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL5561691 0.80 CA1 (0.39) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL9805805 0.80 GRIK1 (0.34) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL9805809 0.80 GRIK1 (0.34) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL5561689 0.80 CA1 (0.39) GRIK1GRIK2GRIA2GRIA4GRIK3
Bucrylate SCHEMBL2789798 0.80 TSHR (0.43) ALDH1A1
SCHEMBL360118 0.77 KDM1A (0.38) GRIK1
SCHEMBL360119 0.77 KDM1A (0.38) GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1640 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116285710-B Instantaneous adhesive and preparation method and application thereof 永一胶粘(中山)有限公司 2023-10-10 CN claimed
CN-116285710-A Instantaneous adhesive and preparation method and application thereof 永一胶粘(中山)有限公司 2023-06-23 CN claimed
CN-116159177-A Adhesive for treating great saphenous vein and preparation method thereof 浙江伽奈维医疗科技有限公司 2023-05-26 CN claimed
CN-109913400-B Artificial tissue precursors and methods for making same 四川蓝光英诺生物科技股份有限公司 2023-03-14 CN claimed
CN-115778449-A Medical adhesive, conveying device and conveying system 赛微医疗科技(上海)有限公司 2023-03-14 CN claimed
US-20220323368-A1 ACTIVE SUBSTANCE DELIVERY SYSTEM WITH DELAYED DELIVERY CAPNOPHARM GMBH (DE) 2022-10-13 US claimed
CN-109735434-B Artificial tissue precursors and methods of making the same 四川蓝光英诺生物科技股份有限公司 2022-09-23 CN claimed
US-20220241213-A1 DELAYED AND SUSTAINED DELIVERY OF ANTICANCER DRUGS CAPNOPHARM GMBH (DE) 2022-08-04 US claimed
US-20220226205-A1 Coated Particles and Their Uses KENVUE BRANDS LLC 2022-07-21 US claimed
EP-3982918-A1 DELAYED AND SUSTAINED DELIVERY OF ANTICANCER DRUGS CAPNOMED GmbH (DE) 2022-04-20 EP claimed
EP-1156812-A1 MULTIPARTICULATE FORMULATION ISIS PHARMACEUTICALS, INC. (US) 2001-11-28 EP claimed
WO-2000050050-A1 MULTIPARTICULATE FORMULATION ISIS PHARMACEUTICALS, INC. (US) 2000-08-31 WO claimed
CN-1261070-A Process for preparing isobutyl alpha-cyanoacrylate ZHU SHIXIN (CN) 2000-07-26 CN claimed
EP-0820300-A1 CONTROLLED RELEASE BIODEGRADABLE NANOPARTICLES CONTAINING INSULIN ELAN CORPORATION PLC (IE) 1998-01-28 EP claimed
US-5641515-A COMPLEX OF INSULIN AND POLYALKYLCYANOACRYLATE OR FREE-INSULIN LOADED POLYALKYLCYANOACRYLATE ELAN CORPORATION, PLC (IE) 1997-06-24 US claimed
WO-1996031231-A1 CONTROLLED RELEASE BIODEGRADABLE NANOPARTICLES CONTAINING INSULIN ELAN CORPORATION, PLC (IE) 1996-10-10 WO claimed
EP-0460806-A2 Electrophotographic sensitive member Kinoshita, Koichi (JP) 1991-12-11 EP claimed
US-5063203-A Anticoagulants, humans CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1991-11-05 US claimed
EP-0269598-B1 THERAPEUTICAL AGENTS AGAINST LEISHMANIOSE N.V. SOPAR S.A. (BE) 1991-04-10 EP claimed
US-4378213-A USING AN ACCELERATOR TO PROMOTE HARDENING MDS PRODUCTS COMPANY, INC. (US) 1983-03-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220226205-A1 Coated Particles and Their Uses CD63, EPCAM, CD44 GRIK1 3062/4885GRIK2 2619/4885GRIA2 1526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.