SCHEMBL256988

SCHEMBL256988

CC1CCN=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13918221 1.00
SCHEMBL16573412 0.65
SCHEMBL1032060 0.62
SCHEMBL154214 0.62
SCHEMBL1033660 0.62
SCHEMBL4118043 0.60
SCHEMBL20073404 0.56
SCHEMBL2784496 0.55
SCHEMBL2784951 0.55
SCHEMBL522287 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304130-A MCL-1 inhibitors 吉利德科学公司 2023-12-29 CN disclosed
US-11701364-B2 Agonists of stimulator of interferon genes sting THE SCRIPPS RESEARCH INSTITUTE (US) 2023-07-18 US disclosed
CN-112118845-B MCL-1 inhibitors 吉利德科学公司 2023-06-13 CN disclosed
US-20220145339-A1 METHOD FOR PREPARATION OF PRIMARY AMINE COMPOUNDS MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2022-05-12 US disclosed
US-20210205321-A1 AGONISTS OF STIMULATOR OF INTERFERON GENES STING THE SCRIPPS RESEARCH INSTITUTE 2021-07-08 US disclosed
CN-112118845-A MCL-1 inhibitors 吉利德科学公司 2020-12-22 CN disclosed
WO-2020120420-A1 METHOD FOR PREPARATION OF PRIMARY AMINE COMPOUNDS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2020-06-18 WO disclosed
EP-2462117-B1 QUINOLINYLOXYPHENYLSULFONAMIDES MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V (DE) 2017-06-28 EP disclosed
EP-2820020-B1 PYRAZOLO-TRIAZINE DERIVATIVES AS SELECTIVE CYCLIN-DEPENDENT KINASE INHIBITORS LEAD DISCOVERY CENTER GMBH (DE) 2016-04-06 EP disclosed
US-9096608-B2 Pharmaceutically active pyrazolo-triazine derivatives LEAD DISCOVERY CENTER GMBH (DE) 2015-08-04 US disclosed
EP-1918286-A1 Thiazolhydrazides for treatment of neurodegenerative diseases MPG Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2008-05-07 EP disclosed
US-20070275962-A1 Heterobicyclic Compounds as Pharmaceutically Active Agents GPC BIOTECH AG (DE) 2007-11-29 US disclosed
US-20070275962-A1 Heterobicyclic Compounds as Pharmaceutically Active Agents GPC BIOTECH AG (DE) 2007-11-29 US disclosed
WO-2007060028-A1 NAPTHYRIDINE COMPOUNDS AS ROCK INHIBITORS GPC BIOTECH AG (DE) 2007-05-31 WO disclosed
EP-1757607-A1 N5-substituted benzo¬2,3|azepino¬4,5-b|indol-6-ones for treating tropical diseases Molisa GmbH (DE) 2007-02-28 EP disclosed
WO-2005023818-A2 HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS GPC BIOTECH AG (DE) 2005-03-17 WO disclosed
US-4950414-A MIXTURE OF POLYISOBUTENE AND PHOSPHETANE ADDITIVE UK-MINERALOLWERKE WENZEL & WEIDMANN, GMBH (DE) 1990-08-21 US disclosed
US-4279761-A LUBRICANT ADDITIVE CIBA-GEIGY CORPORATION (US) 1981-07-21 US disclosed
US-4244827-A AS STABILIZING ADDITIVES FOR LUBRICANTS CIBA-GEIGY CORPORATION (US) 1981-01-13 US disclosed
US-4080307-A AMMONIUM SALTS OF 1,3-OXA- OR 1,3-THIA-PHOSPHETANES CIBA-GEIGY AG (CH) 1978-03-21 US disclosed