Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2566643 | 0.83 | SMN1; SMN2 (0.40) | HPGDSMN1; SMN2TSHRALDH1A1KDM4E | |
| SCHEMBL3036022 | 0.82 | F10 (0.36) | HPGDF10SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL13012349 | 0.82 | F10 (0.36) | HPGDF10SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL13012340 | 0.74 | TMIGD3 (0.35) | HPGDF10SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL3774208 | 0.70 | HPGD (0.42) | HPGDSMN1; SMN2TSHRALDH1A1KDM4E | |
| SCHEMBL2566642 | 0.70 | HPGD (0.42) | HPGDSMN1; SMN2TSHRALDH1A1KDM4E | |
| SCHEMBL14477387 | 0.70 | HPGD (0.42) | HPGDSMN1; SMN2TSHRALDH1A1KDM4E | |
| SCHEMBL2569570 | 0.70 | HTT (0.45) | HPGDSMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL2566574 | 0.69 | KMT2A (0.44) | ALDH1A1KMT2AMEN1NPSR1LMNA | |
| SCHEMBL13012380 | 0.68 | KMT2A (0.42) | HPGDSMN1; SMN2TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |