Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 16/20 | 0.48 |
| ▸ | ATRIP | Q8WXE1 | 9/20 | 0.48 |
| ▸ | MTOR | P42345 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23629220 | 0.89 | ATR (0.47) | ATRATRIPMTOR | |
| SCHEMBL23629225 | 0.80 | ATR (0.45) | ATRATRIPMTOR | |
| SCHEMBL23629242 | 0.75 | ATR (0.54) | ATRATRIPMTOR | |
| SCHEMBL28580527 | 0.75 | ATR (0.54) | ATRATRIPMTOR | |
| SCHEMBL23408533 | 0.75 | ATR (0.47) | ATRATRIPMTOR | |
| SCHEMBL24024179 | 0.74 | ATR (0.45) | ATRATRIPMTOR | |
| SCHEMBL19146761 | 0.73 | ATR (0.62) | ATRATRIP | |
| SCHEMBL19127005 | 0.73 | ATR (0.62) | ATRATRIP | |
| SCHEMBL29261234 | 0.72 | ATR (0.52) | ATRATRIPMTOR | |
| SCHEMBL29738249 | 0.72 | MTOR (0.48) | ATRATRIPMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846904-B1 | 5-MORPHOLIN-4-YL-PYRAZOLO[4,3-B]PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-05-31 | — | — | EP | disclosed |