Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25702903 | 0.85 | CYP2D6 (0.48) | CYP2D6CYP2C19HRH3CYP2C9ALDH1A1 | |
| SCHEMBL18711923 | 0.83 | PIK3CD (0.47) | HRH3ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL25708207 | 0.82 | CYP2D6 (0.46) | CYP2D6CYP2C19HRH3CYP2C9ALDH1A1 | |
| SCHEMBL26783934 | 0.79 | USP2 (0.60) | CYP2D6CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL15544126 | 0.77 | USP2 (0.58) | CYP2D6CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL20719249 | 0.75 | CYP2D6 (0.41) | CYP2D6CYP2C19HRH3CYP2C9ALDH1A1 | |
| SCHEMBL24918193 | 0.74 | CYP2C9 (0.57) | CYP2D6CYP2C19HRH3CYP2C9ALDH1A1 | |
| SCHEMBL25701698 | 0.74 | CYP2D6 (0.51) | CYP2D6CYP2C19HRH3CYP2C9ALDH1A1 | |
| SCHEMBL27381148 | 0.73 | CYP2C9 (0.45) | CYP2D6CYP2C19HRH3CYP2C9ALDH1A1 | |
| SCHEMBL18711490 | 0.73 | USP2 (0.55) | CYP2D6CYP2C19CYP2C9ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107606-A1 | BCL-XL/BCL-2 DUAL DEGRADERS FOR TREATMENT OF CANCERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-06-15 | — | — | WO | disclosed |