SCHEMBL257019

SCHEMBL257019

CC1C=CN=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20020053 0.69
SCHEMBL24141563 0.65
SCHEMBL23295197 0.60
SCHEMBL14522839 0.55
SCHEMBL1382945 0.55
SCHEMBL6394541 0.55
SCHEMBL11957633 0.52
SCHEMBL12992997 0.47
SCHEMBL6324015 0.46
SCHEMBL790973 0.46

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0012241-B1 USE OF DISAZOMETHINE COMPOUNDS FOR THE DYEING OF THERMOPLASTIC POLYESTERS IN THE MASS HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-16 EP claimed
US-20230271994-A1 MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS UNIV YALE (US) 2023-08-31 US disclosed
US-11658322-B2 Membranes and anion conductive polymers MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-05-23 US disclosed
US-20220411403-A1 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS AJAX THERAPEUTICS, INC. 2022-12-29 US disclosed
US-20220145339-A1 METHOD FOR PREPARATION OF PRIMARY AMINE COMPOUNDS MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2022-05-12 US disclosed
US-20220025351-A1 PRODUCTION METHOD FOR IMMOBILIZED MICROORGANISMS AND PRODUCTION METHOD FOR AMINO ACID USING THE SAME KANEKA CORPORATION (JP) 2022-01-27 US disclosed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
US-20210135265-A1 ANION CONDUCTIVE POLYMERS AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-05-06 US disclosed
WO-2020120420-A1 METHOD FOR PREPARATION OF PRIMARY AMINE COMPOUNDS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2020-06-18 WO disclosed
CN-109415457-A The method for preparing functionalized polymeric 株式会社普利司通 2019-03-01 CN disclosed
US-20100048567-A1 Inhibitors of syk and JAK protein kinases PORTOLA PHARMACEUTICALS INC. (US) 2010-02-25 US disclosed
US-7598243-B2 inhibit atherosclerotic lesion formation and pathological progression by impairing monocyte recruitment and differentiation in the arterial wall; antiinflammatory, anticarcinogenic agent; autoimmune diseases MERCK & CO., INC. (US) 2009-10-06 US disclosed
WO-2009003700-A1 LUMINESCENT METAL COMPLEXES FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2009-01-08 WO disclosed
EP-1918375-A1 D-AMINO ACID OXIDASE, AND METHOD FOR PRODUCTION OF L-AMINO ACID, 2-OXO ACID OR CYCLIC IMINE Kaneka Corporation (JP) 2008-05-07 EP disclosed
US-20080081803-A1 Heterocyclic cyclopentyl tetrahydroisoquinoline and tetrahydropyridopyridine modulators of chemokine receptor activity MERCK SHARP & DOHME CORP. 2008-04-03 US disclosed
US-20070275962-A1 Heterobicyclic Compounds as Pharmaceutically Active Agents GPC BIOTECH AG (DE) 2007-11-29 US disclosed
US-20070275962-A1 Heterobicyclic Compounds as Pharmaceutically Active Agents GPC BIOTECH AG (DE) 2007-11-29 US disclosed
WO-2007060028-A1 NAPTHYRIDINE COMPOUNDS AS ROCK INHIBITORS GPC BIOTECH AG (DE) 2007-05-31 WO disclosed
EP-1757607-A1 N5-substituted benzo¬2,3|azepino¬4,5-b|indol-6-ones for treating tropical diseases Molisa GmbH (DE) 2007-02-28 EP disclosed
WO-2005023818-A2 HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS GPC BIOTECH AG (DE) 2005-03-17 WO disclosed