Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13211408 | 0.85 | METAP1 (0.64) | METAP1BRD4NAMPTTDP2ATR | |
| SCHEMBL31047027 | 0.85 | METAP1 (0.64) | METAP1BRD4NAMPTTDP2ATR | |
| SCHEMBL30937705 | 0.85 | METAP1 (0.64) | METAP1BRD4NAMPTTDP2ATR | |
| SCHEMBL4345991 | 0.83 | METAP1 (0.62) | METAP1BRD4NAMPTTDP2ATR | |
| SCHEMBL1580424 | 0.80 | METAP1 (0.55) | METAP1BRD4NAMPTTDP2ATR | |
| SCHEMBL30413190 | 0.80 | METAP1 (0.55) | METAP1BRD4NAMPTTDP2ATR | |
| SCHEMBL30937714 | 0.80 | METAP1 (0.59) | METAP1BRD4NAMPTTDP2ATR | |
| SCHEMBL4906896 | 0.79 | BRD4 (0.70) | METAP1BRD4TDP2ATRBRD9 | |
| SCHEMBL6868944 | 0.79 | METAP1 (0.56) | METAP1NAMPTTDP2ATRBRD9 | |
| SCHEMBL3243855 | 0.79 | METAP1 (0.56) | METAP1BRD4NAMPTTDP2ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094830-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |