SCHEMBL25713304

SCHEMBL25713304

c1ccc2cc(-c3ccc(N(c4ccc(-c5ccc6ccccc6c5)cc4)c4cccc5oc6cccnc6c45)cc3)ccc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.38
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
POLB P06746 1/20 0.37
CYP17A1 P05093 1/20 0.37
CYP19A1 P11511 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
DYRK1A Q13627 1/20 0.35
SIRT2 Q8IXJ6 2/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
TSHR P16473 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
LMNA P02545 2/20 0.34
TP53 P04637 2/20 0.34
MAPT P10636 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HSD17B10 Q99714 2/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25713202 0.98 CYP17A1 (0.38) KDM4ENPC1RAB9APOLBCYP17A1
SCHEMBL25713188 0.93 KDM4E (0.34) KDM4ENPC1CYP17A1CYP19A1CYP11B1
SCHEMBL25713363 0.89 GRM4 (0.35) KDM4ENPC1RAB9APOLBDYRK1A
SCHEMBL25713050 0.87 MAPK14 (0.34) KDM4ENPC1MEN1KMT2AL3MBTL1
SCHEMBL25713123 0.87 MAPK14 (0.34) KDM4ENPC1MEN1KMT2AL3MBTL1
SCHEMBL25713165 0.87 TRPV1 (0.32) KDM4EMAPTMEN1KMT2AL3MBTL1
SCHEMBL25713098 0.87 TRPV1 (0.32) KDM4EMAPTMEN1KMT2AL3MBTL1
SCHEMBL25713107 0.86 MAPK14 (0.33) KDM4EMEN1KMT2AL3MBTL1
SCHEMBL25713032 0.86 MAPK14 (0.33) KDM4EMEN1KMT2AL3MBTL1
SCHEMBL24056243 0.85 NPC1 (0.37) KDM4ENPC1RAB9APOLBCYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157159-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-05-18 US disclosed
US-20230157159-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157159-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME NR0B1, AHR, ARL1 KDM4E 2899/4885NPC1 2413/4885RAB9A 2249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.