Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 3/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25714869 | 0.85 | KDR (0.47) | KDRNTRK1SRCNTRK2FGFR1 | |
| SCHEMBL25715556 | 0.80 | KDR (0.46) | KDRNTRK1SRCNTRK2FGFR1 | |
| SCHEMBL25715613 | 0.80 | KDR (0.45) | KDRNTRK1SRCNTRK2FGFR1 | |
| SCHEMBL25715673 | 0.78 | CDK2 (0.45) | KDRNTRK1SRCNTRK2FGFR1 | |
| SCHEMBL25715709 | 0.77 | BTK (0.48) | KDRNTRK1SRCNTRK2FGFR1 | |
| SCHEMBL25716911 | 0.77 | KDR (0.44) | KDRNTRK1SRCNTRK2FGFR1 | |
| SCHEMBL25715487 | 0.77 | FGFR1 (0.52) | KDRNTRK1SRCNTRK2FGFR1 | |
| SCHEMBL25715699 | 0.77 | FGFR1 (0.46) | KDRNTRK1SRCNTRK2FGFR1 | |
| SCHEMBL30586220 | 0.76 | BTK (0.45) | KDRNTRK1SRCNTRK2FGFR1 | |
| SCHEMBL22676014 | 0.76 | BTK (0.45) | KDRNTRK1SRCNTRK2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |