SCHEMBL25715514

SCHEMBL25715514

COc1cc(C)cc2cc(-c3c(Cl)c(OC)n4ncnc(N)c34)sc12

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 20/20 0.70
▸ FGFR3 P22607 15/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25715515 0.84 FGFR1 (0.62) FGFR1FGFR3
SCHEMBL15019843 0.83 FGFR1 (0.72) FGFR1FGFR3
SCHEMBL15020408 0.83 FGFR1 (0.84) FGFR1FGFR3
SCHEMBL15023095 0.82 FGFR1 (1.00) FGFR1FGFR3
SCHEMBL15023934 0.81 FGFR1 (1.00) FGFR1FGFR3
SCHEMBL16577572 0.81 FGFR1 (0.71) FGFR1FGFR3
SCHEMBL15023381 0.80 FGFR1 (1.00) FGFR1FGFR3
SCHEMBL15023094 0.80 FGFR1 (1.00) FGFR1FGFR3
SCHEMBL15019848 0.80 FGFR1 (0.70) FGFR1FGFR3
Hydrochloric Acid SCHEMBL15023225 0.80 FGFR1 (0.98) FGFR1FGFR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023104035-A1 SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 英矽智能科技(上海)有限公司 2023-06-15 — — WO disclosed
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