Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.44 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.44 |
| ▸ | HINT1 | P49773 | 2/20 | 0.43 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 3/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22348826 | 0.93 | POLB (0.57) | CYP3A4CYP2C9POLBTAS1R3TAS1R1 | |
| SCHEMBL23187769 | 0.93 | POLB (0.57) | CYP3A4CYP2C9POLBTAS1R3TAS1R1 | |
| SCHEMBL29944545 | 0.93 | POLB (0.57) | CYP3A4CYP2C9POLBTAS1R3TAS1R1 | |
| SCHEMBL21162576 | 0.93 | POLB (0.57) | CYP3A4CYP2C9POLBTAS1R3TAS1R1 | |
| SCHEMBL17198467 | 0.92 | CYP3A4 (0.48) | CYP3A4CYP2C9POLBTAS1R3TAS1R1 | |
| SCHEMBL17198258 | 0.92 | CYP3A4 (0.48) | CYP3A4CYP2C9POLBTAS1R3TAS1R1 | |
| SCHEMBL17198510 | 0.92 | CYP3A4 (0.48) | CYP3A4CYP2C9POLBTAS1R3TAS1R1 | |
| SCHEMBL17198632 | 0.92 | CYP3A4 (0.48) | CYP3A4CYP2C9POLBTAS1R3TAS1R1 | |
| SCHEMBL17198533 | 0.92 | CYP3A4 (0.48) | CYP3A4CYP2C9POLBTAS1R3TAS1R1 | |
| SCHEMBL17198257 | 0.92 | CYP3A4 (0.48) | CYP3A4CYP2C9POLBTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |