Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.65 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.65 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 6/20 | 0.42 |
| ▸ | MET | P08581 | 4/20 | 0.42 |
| ▸ | KIT | P10721 | 3/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 2/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715487 | 0.90 | FGFR1 (0.52) | FGFR1FGFR3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25715486 | 0.85 | FGFR1 (0.44) | FGFR1FGFR3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31213932 | 0.85 | FGFR1 (0.66) | FGFR1FGFR3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL24773300 | 0.84 | CYP3A4 (0.73) | FGFR1FGFR3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30680174 | 0.84 | CYP3A4 (0.73) | FGFR1FGFR3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31213902 | 0.82 | FGFR1 (0.59) | FGFR1FGFR3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31214014 | 0.81 | CYP3A4 (0.61) | FGFR1FGFR3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31213876 | 0.80 | FGFR1 (0.60) | FGFR1FGFR3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25715485 | 0.80 | CYP2C9 (0.45) | FGFR1FGFR3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31213957 | 0.79 | CYP3A4 (0.59) | FGFR1FGFR3CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |