Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.61 |
| ▸ | CA1 | P00915 | 7/20 | 0.61 |
| ▸ | CA2 | P00918 | 7/20 | 0.61 |
| ▸ | CA9 | Q16790 | 7/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | ITK | Q08881 | 2/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 4/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463829 | 1.00 | CA12 (0.61) | CA12CA1CA2CA9TSHR | |
| SCHEMBL30448576 | 1.00 | CA12 (0.61) | CA12CA1CA2CA9TSHR | |
| SCHEMBL25718490 | 0.99 | CA1 (0.60) | CA12CA1CA2CA9TSHR | |
| SCHEMBL30448898 | 0.99 | CA1 (0.60) | CA12CA1CA2CA9TSHR | |
| SCHEMBL10288896 | 0.95 | CA1 (0.59) | CA12CA1CA2CA9TSHR | |
| SCHEMBL29379579 | 0.91 | CA12 (0.58) | CA12CA1CA2CA9TSHR | |
| SCHEMBL541782 | 0.91 | CA12 (0.58) | CA12CA1CA2CA9TSHR | |
| SCHEMBL24061179 | 0.88 | CA1 (0.55) | CA12CA1CA2CA9EGFR | |
| SCHEMBL30595926 | 0.88 | CA1 (0.55) | CA12CA1CA2CA9EGFR | |
| SCHEMBL18041357 | 0.87 | BCHE (0.52) | CA12CA1CA2CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091565-A1 | NSD2-TARGETED CHEMICAL DEGRADERS AND COMPOSITIONS AND METHODS OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-05-25 | — | — | WO | disclosed |