Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 5/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966816 | 0.88 | PDGFRB (0.59) | FGFR2PDGFRBKDRPDGFRA | |
| SCHEMBL25719208 | 0.88 | FGFR2 (0.49) | AXLFGFR2PDGFRBKDRPDGFRA | |
| SCHEMBL25719101 | 0.85 | FGFR2 (0.48) | AXLFGFR2PDGFRBKDRPDGFRA | |
| SCHEMBL24240698 | 0.82 | FGFR2 (0.62) | AXLFGFR2PDGFRBKDRPDGFRA | |
| SCHEMBL30465735 | 0.81 | FGFR2 (0.44) | AXLFGFR2PDGFRBKDRPDGFRA | |
| SCHEMBL25297071 | 0.80 | KDR (0.47) | AXLFGFR2PDGFRBKDRPDGFRA | |
| SCHEMBL25719157 | 0.80 | FGFR2 (0.51) | AXLFGFR2KDRPDGFRAEGFR | |
| SCHEMBL25261932 | 0.79 | PDGFRA (0.47) | AXLFGFR2PDGFRBKDRPDGFRA | |
| SCHEMBL30565662 | 0.79 | PDGFRA (0.47) | AXLFGFR2PDGFRBKDRPDGFRA | |
| SCHEMBL30465792 | 0.79 | FLT3 (0.46) | AXLFGFR2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114809-A1 | INHIBITORS OF MET KINASE | KINNATE BIOPHARMA INC. (US) | 2023-06-22 | — | — | WO | disclosed |