Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 10/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23235763 | 0.94 | MAOB (0.63) | GRM5MAOBFFAR1FFAR4MAOA | |
| SCHEMBL13232461 | 0.88 | GRM5 (0.62) | GRM5MAOBFFAR1FFAR4MAOA | |
| SCHEMBL1248693 | 0.85 | MAOB (0.66) | GRM5MAOBFFAR1FFAR4MAOA | |
| SCHEMBL13462745 | 0.85 | MAOB (0.55) | GRM5MAOBFFAR1FFAR4MAOA | |
| SCHEMBL15474234 | 0.85 | MAOB (0.56) | GRM5MAOBFFAR1FFAR4MAOA | |
| SCHEMBL23235825 | 0.84 | MAOB (0.65) | GRM5MAOBFFAR1FFAR4MAOA | |
| SCHEMBL15344203 | 0.84 | MAOB (0.80) | GRM5MAOBFFAR1MAOA | |
| SCHEMBL1547975 | 0.84 | MAOB (0.74) | MAOBFFAR1MAOA | |
| SCHEMBL4701103 | 0.83 | FFAR1 (0.59) | GRM5MAOBFFAR1FFAR4MAOA | |
| SCHEMBL23541335 | 0.83 | FFAR1 (0.51) | GRM5MAOBFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091873-A1 | GRAM-NEGATIVE SPECIFIC ANTIBIOTICS SPARING EFFECT ON GUT MICROBIOME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-25 | — | — | WO | disclosed |