Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STT3A | P46977 | 1/20 | 0.66 |
| ▸ | STT3B | Q8TCJ2 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25725975 | 0.91 | STT3A (0.54) | STT3ASTT3BL3MBTL1TSHRMAPK1 | |
| SCHEMBL25727307 | 0.89 | STT3A (0.62) | STT3ASTT3BL3MBTL1TSHRMAPK1 | |
| SCHEMBL25725970 | 0.89 | STT3A (0.78) | STT3ASTT3BL3MBTL1TSHRMAPK1 | |
| SCHEMBL25725973 | 0.88 | STT3A (0.51) | STT3ASTT3BL3MBTL1TSHRMAPK1 | |
| SCHEMBL30466368 | 0.88 | STT3A (0.51) | STT3ASTT3BL3MBTL1TSHRMAPK1 | |
| SCHEMBL25231014 | 0.88 | STT3A (0.51) | STT3ASTT3BL3MBTL1TSHRMAPK1 | |
| SCHEMBL25726231 | 0.84 | STT3A (0.47) | STT3ASTT3BL3MBTL1TSHRMAPK1 | |
| SCHEMBL25727234 | 0.84 | STT3A (0.54) | STT3ASTT3BL3MBTL1TSHRMAPK1 | |
| SCHEMBL25726323 | 0.83 | STT3A (0.73) | STT3ASTT3BL3MBTL1TSHRMAPK1 | |
| SCHEMBL25726798 | 0.82 | STT3A (0.53) | STT3ASTT3BL3MBTL1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114428-A1 | HETEROCYCLE DERIVATIVES FOR THE TREATMENT OF DISEASE | Vir Biotechnology, Inc. (US) | 2023-06-22 | — | — | WO | disclosed |