SCHEMBL25726324

SCHEMBL25726324

COC[C@H]1COCCN1C(=O)CN(C)S(=O)(=O)c1ccc(N2CCCC2)c(-c2cc3ccc(C)cc3[nH]2)c1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STT3A P46977 1/20 0.82
STT3B Q8TCJ2 1/20 0.82
GFER P55789 1/20 0.36
TSHR P16473 4/20 0.35
HTT P42858 2/20 0.35
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 3/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 2/20 0.33
ALOX15 P16050 1/20 0.33
RAB9A P51151 1/20 0.33
AKT1 P31749 1/20 0.32
ALPL P05186 1/20 0.32
POLB P06746 1/20 0.32
ALPI P09923 1/20 0.32
ALPG P10696 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CASP1 P29466 1/20 0.32
CASP3 P42574 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25726322 1.00 STT3A (0.82) STT3ASTT3BGFERTSHRHTT
SCHEMBL25726328 0.92 STT3A (0.85) STT3ASTT3BGFERTSHRHTT
SCHEMBL25733879 0.92 STT3A (0.85) STT3ASTT3BGFERTSHRHTT
SCHEMBL25725788 0.90 STT3A (1.00) STT3ASTT3BGFERTSHRHTT
SCHEMBL25726108 0.90 STT3A (1.00) STT3ASTT3BGFERTSHRHTT
SCHEMBL25726112 0.90 STT3A (1.00) STT3ASTT3BGFERTSHRHTT
SCHEMBL25725970 0.85 STT3A (0.78) STT3ASTT3BGFERTSHRHTT
SCHEMBL25726199 0.85 STT3A (0.78) STT3ASTT3BGFERTSHRHTT
SCHEMBL25733919 0.84 STT3A (0.66) STT3ASTT3BGFERTSHRHTT
SCHEMBL25726165 0.83 STT3A (0.68) STT3ASTT3BGFERTSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023114428-A1 HETEROCYCLE DERIVATIVES FOR THE TREATMENT OF DISEASE Vir Biotechnology, Inc. (US) 2023-06-22 WO disclosed