Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.38 |
| ▸ | FDPS | P14324 | 9/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14778378 | 1.00 | TSHR (0.42) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL12336367 | 1.00 | TSHR (0.42) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL3249837 | 1.00 | TSHR (0.42) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL14778439 | 1.00 | TSHR (0.42) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL14778077 | 1.00 | TSHR (0.42) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL4451444 | 0.97 | TSHR (0.37) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL6160701 | 0.89 | TSHR (0.36) | TSHRTHRBFDPS | |
| Hydrochloric Acid SCHEMBL9418676 | 0.84 | HTT (0.56) | — | |
| Methyl Nonyl Ketone SCHEMBL21328499 | 0.82 | CES1 (0.42) | TSHRCES2 | |
| SCHEMBL95578 | 0.79 | TSHR (0.46) | TSHRTHRBGGPS1SMPD1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1140349-C | Catalyst for conversion of ethylene into light alpha olefins | — | 2004-03-03 | — | — | CN | claimed |
| EP-0860411-B1 | Improved catalytic composition for the conversion of ethylene to alpha olefins | INST FRANCAIS DU PETROLE (FR) | 2003-10-29 | — | — | EP | claimed |
| CN-1107545-C | Improved catalytic composition and process for converting ethylene to light alpha olefins | INST FRANCAIS DU PETROLE (FR) | 2003-05-07 | — | — | CN | claimed |
| US-6221986-B1 | CATALYTIC OLIGOMERIZATION | INSTITUT FRANCAIS DU PETROLE (FR) | 2001-04-24 | — | — | US | claimed |
| US-6103654-A | Catalytic composition and a process for converting ethylene to light alpha olefins | INSTITUT FRANCAIS DU PETROLE (FR) | 2000-08-15 | — | — | US | claimed |
| CN-1047374-C | Process for converting ethylene to light alpha-olefins | INST FRANCAIS DU PETROLE (FR) | 1999-12-15 | — | — | CN | claimed |
| CN-1229696-A | Catalyst for conversion of ethylene into light alpha olefins | INST FRANCAIS DU PETROLE (FR) | 1999-09-29 | — | — | CN | claimed |
| CN-1195580-A | Improved catalytic composition and process for converting ethylene to light alpha olefins | INST FRANCAIS DU PETROLE (FR) | 1998-10-14 | — | — | CN | claimed |
| EP-0578541-B1 | Process for the preparation of light alpha-olefines by oligomerisation of ethylene | INST FRANCAIS DU PETROLE (FR) | 1997-12-03 | — | — | EP | claimed |
| US-5496783-A | CATALYSIS WITH MIXTURE OF ZIRCONIUM COMPOUND, ACETAL OR KETAL, AND ORGANOALUMINUM BROMIDE OR CHLORIDE | INSTITUT FRANCAIS DU PETROLE (FR) | 1996-03-05 | — | — | US | claimed |
| US-5345023-A | Zirconium coordination catalysts with acetals and ketals | INSTITUT FRANCAIS DU PETROLE (FR) | 1994-09-06 | — | — | US | claimed |
| CN-1083465-A | Method for producing light alpha olefin by ethylene oligomerization | INST FRANCAIS DU PETROLE (FR) | 1994-03-09 | — | — | CN | claimed |
| JP-4095039-A | — | — | None | — | — | JP | disclosed |
| CN-103012628-A | Solid catalyst for olefin polymerization and process for producing olefin polymer | SUMITOMO CHEMICAL CO | 2013-04-03 | — | — | CN | disclosed |
| US-20130072648-A1 | SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-21 | — | — | US | disclosed |
| US-20120289502-A1 | IMIDAZOLE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-11-15 | — | — | US | disclosed |
| EP-0045524-B1 | 22-ARYLSULFONYL-24,25-DIHYDROXYCHOLESTANES AND PROCESS FOR PREPARING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1983-10-19 | — | — | EP | disclosed |
| EP-0060077-A1 | Beta-lactam antibiotics, their preparation and use | BEECHAM GROUP PLC (GB) | 1982-09-15 | — | — | EP | disclosed |
| US-4344888-A | 24,25-Dihydroxycholestans and process for preparing the same | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1982-08-17 | — | — | US | disclosed |
| EP-0045524-A1 | 22-Arylsulfonyl-24,25-dihydroxycholestanes and process for preparing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289502-A1 | IMIDAZOLE DERIVATIVES | CNR1, CNR2, ARRB1 | TSHR 478/4885THRB 481/4885GGPS1 2707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.