Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576401 | 0.95 | BACE1 (0.73) | BACE1CTSD | |
| SCHEMBL2575485 | 0.89 | BACE1 (0.73) | BACE1CTSD | |
| SCHEMBL2561410 | 0.87 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL2581013 | 0.86 | BACE1 (0.80) | BACE1CTSD | |
| SCHEMBL7711676 | 0.86 | BACE1 (0.78) | BACE1CTSD | |
| SCHEMBL7710740 | 0.85 | BACE1 (0.91) | BACE1CTSD | |
| SCHEMBL7711743 | 0.85 | BACE1 (0.63) | BACE1CTSD | |
| SCHEMBL2572696 | 0.84 | BACE1 (0.79) | BACE1CTSD | |
| SCHEMBL7713018 | 0.84 | BACE1 (0.71) | BACE1CTSD | |
| SCHEMBL7710636 | 0.84 | BACE1 (0.69) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130741-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011130741-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |