Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.60 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 3/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | IL1B | P01584 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.51 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23696885 | 0.93 | CRBN (0.60) | CRBNDDB1MAP1LC3BSTAT3TNF | |
| SCHEMBL25878614 | 0.92 | CRBN (0.58) | CRBNDDB1MAP1LC3BSTAT3TNF | |
| SCHEMBL24229227 | 0.91 | CRBN (0.62) | CRBNDDB1STAT3TNFIL1B | |
| SCHEMBL25894864 | 0.91 | CRBN (0.62) | CRBNDDB1MAP1LC3BSTAT3TNF | |
| SCHEMBL25731159 | 0.90 | DDB1 (0.65) | CRBNDDB1MAP1LC3BSTAT3TNF | |
| SCHEMBL22835222 | 0.90 | CRBN (0.62) | CRBNDDB1MAP1LC3BSTAT3TNF | |
| SCHEMBL23539211 | 0.88 | CRBN (0.65) | CRBNDDB1MAP1LC3BSTAT3TNF | |
| SCHEMBL22835837 | 0.87 | CRBN (0.68) | CRBNDDB1MAP1LC3BSTAT3CA2 | |
| SCHEMBL25878607 | 0.86 | CRBN (0.60) | CRBNDDB1MAP1LC3BSTAT3TNF | |
| SCHEMBL23672358 | 0.86 | CRBN (0.58) | CRBNDDB1MAP1LC3BSTAT3CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144292-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230144292-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | CRBN 187/4885DDB1 1267/4885MAP1LC3B 1569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.