SCHEMBL25734348

SCHEMBL25734348

CSc1cccc2c(C(C)(C)NC(=O)[C@H]3[C@@H]4CNC[C@@]43C)nn(C)c12

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 20/20 0.52
SSTR1 P30872 5/20 0.52
SSTR2 P30874 3/20 0.42
SSTR3 P32745 3/20 0.42
SSTR5 P35346 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24057356 1.00 SSTR4 (0.52) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL24047659 0.88 SSTR4 (0.67) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL24048369 0.88 SSTR4 (0.67) SSTR4SSTR1SSTR2SSTR3SSTR5
Formic Acid SCHEMBL30449133 0.85 SSTR4 (0.62) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL25735300 0.83 SSTR4 (0.44) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL24048320 0.83 SSTR4 (0.65) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL25233504 0.81 SSTR4 (0.76) SSTR4SSTR1
SCHEMBL30023497 0.81 SSTR4 (0.76) SSTR4SSTR1
SCHEMBL24057990 0.81 SSTR4 (0.76) SSTR4SSTR1
SCHEMBL25276190 0.81 SSTR4 (0.76) SSTR4SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192683-A1 FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF GUANGZHOU FERMION TECHNOLOGY CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192683-A1 FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF SSTR4, SSTR3, NPY4R SSTR4 1/4885SSTR1 4/4885SSTR2 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.