SCHEMBL25735645

SCHEMBL25735645

c1ccc(-c2ncc(-c3cccnc3)nc2-c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.56
ATR Q13535 5/20 0.56
CYP2A6 P11509 4/20 0.55
PIM1 P11309 1/20 0.51
PIM3 Q86V86 1/20 0.51
PIM2 Q9P1W9 1/20 0.51
MAPK1 P28482 2/20 0.50
RAB9A P51151 2/20 0.50
ABL1 P00519 1/20 0.50
EGFR P00533 1/20 0.50
PRKCA P17252 1/20 0.50
PRKCD Q05655 1/20 0.50
NPC1 O15118 1/20 0.50
HSP90AA1 P07900 1/20 0.49
HSP90AB1 P08238 1/20 0.49
PTK2 Q05397 1/20 0.49
CYP3A4 P08684 3/20 0.48
ALDH1A1 P00352 2/20 0.48
CYP1A2 P05177 1/20 0.48
GPR84 Q9NQS5 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30785740 1.00 CYP19A1 (0.56) CYP19A1ATRCYP2A6PIM1PIM3
SCHEMBL29886664 0.85 ATR (0.71) CYP19A1ATRCYP2A6HSP90AA1HSP90AB1
SCHEMBL87574 0.85 CKS1B (0.55) ATRMAPK1RAB9ANPC1ALDH1A1
SCHEMBL28243355 0.83 CKS1B (0.53) ATRMAPK1RAB9ANPC1ALDH1A1
SCHEMBL27816089 0.83 CKS1B (0.53) ATRMAPK1RAB9ANPC1ALDH1A1
SCHEMBL29406280 0.83 CKS1B (0.53) ATRMAPK1RAB9ANPC1ALDH1A1
SCHEMBL19820819 0.82 CKS1B (0.57) ATRMAPK1RAB9ANPC1ALDH1A1
SCHEMBL16750246 0.81 CKS1B (0.52) ATRMAPK1RAB9ANPC1ALDH1A1
SCHEMBL7220134 0.77 CYP19A1 (0.54) CYP19A1ATRCYP2A6PIM1PIM3
SCHEMBL29832898 0.76 MAPK1 (0.59) CYP19A1ATRCYP2A6MAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4198026-A1 COMPOUNDS FOR USE IN SEMICONDUCTIONG MATERIALS SUITABLE FOR ELECTRONIC DEVICES Novaled GmbH (DE) 2023-06-21 EP disclosed