Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.47 |
| ▸ | CDK2 | P24941 | 6/20 | 0.38 |
| ▸ | CDK9 | P50750 | 5/20 | 0.38 |
| ▸ | CDK7 | P50613 | 3/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 4/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21473010 | 0.92 | CSNK2A1 (0.52) | CSNK2A1CDK2CDK9CDK7CDK4 | |
| SCHEMBL25736235 | 0.91 | CSNK2A1 (0.45) | CSNK2A1CDK2CDK9CDK7CDK4 | |
| SCHEMBL20549636 | 0.89 | CSNK2A1 (0.46) | CSNK2A1CDK2CDK9CDK7TTK | |
| SCHEMBL25736291 | 0.88 | CSNK2A1 (0.44) | CSNK2A1CDK9TTKCYP3A4PIM1 | |
| SCHEMBL18122196 | 0.88 | CSNK2A1 (0.44) | CSNK2A1CDK9TTKCYP3A4PIM1 | |
| SCHEMBL18122197 | 0.85 | CSNK2A1 (0.46) | CSNK2A1CDK2CDK9CDK7CDK4 | |
| SCHEMBL20549671 | 0.85 | CSNK2A1 (0.46) | CSNK2A1CDK2CDK9CDK7CDK4 | |
| SCHEMBL20550115 | 0.84 | CSNK2A1 (0.46) | CSNK2A1CDK2CDK9CDK7CDK4 | |
| SCHEMBL20550117 | 0.84 | CSNK2A1 (0.46) | CSNK2A1CDK2CDK9CDK7CDK4 | |
| SCHEMBL20550119 | 0.76 | CSNK2A1 (0.43) | CSNK2A1CDK2CDK9CDK7CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183240-A9 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183240-A9 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | CDK3, CDK13, CDK1 | CSNK2A1 403/4885CDK2 6/4885CDK9 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.