Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 6/20 | 0.40 |
| ▸ | CCNH | P51946 | 6/20 | 0.40 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.40 |
| ▸ | MELK | Q14680 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | CCNK | O75909 | 2/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.40 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18313497 | 0.85 | CDK2 (0.53) | CDK7CCNHMNAT1MELKCDK2 | |
| SCHEMBL20549702 | 0.85 | CDK2 (0.53) | CDK7CCNHMNAT1MELKCDK2 | |
| SCHEMBL20549657 | 0.82 | CDK2 (0.51) | CDK7CCNHMNAT1MELKCDK2 | |
| SCHEMBL18313283 | 0.82 | CDK2 (0.51) | CDK7CCNHMNAT1MELKCDK2 | |
| SCHEMBL20549662 | 0.79 | CDK2 (0.58) | CDK7CCNHMNAT1CDK2CCNK | |
| SCHEMBL18313115 | 0.79 | CDK2 (0.58) | CDK7CCNHMNAT1CDK2CCNK | |
| SCHEMBL25736238 | 0.77 | CDK2 (0.51) | CDK7CCNHMNAT1CDK2CCNK | |
| SCHEMBL21473063 | 0.77 | CSNK2A1 (0.57) | CDK7CCNHMNAT1CDK2CCNK | |
| SCHEMBL18313623 | 0.76 | CSNK2A1 (0.56) | CDK7CCNHMNAT1MELKCDK2 | |
| SCHEMBL20288862 | 0.76 | CDK2 (0.54) | CDK7CCNHMNAT1CDK2CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183240-A9 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183240-A9 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | CDK3, CDK13, CDK1 | CDK7 12/4885CCNH 46/4885MNAT1 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.