Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706591 | 0.85 | PDE3B (0.43) | METAP2TNKS2TNKSCDK5CDK9 | |
| SCHEMBL2798886 | 0.79 | KDM4E (0.62) | METAP2TNKS2TNKSHPGDTP53 | |
| SCHEMBL29892996 | 0.79 | KDM4E (0.62) | METAP2TNKS2TNKSHPGDTP53 | |
| SCHEMBL29171685 | 0.78 | TP53 (0.47) | METAP2TNKS2CDK5CDK9CAMK2A | |
| SCHEMBL29831055 | 0.78 | KDM4E (0.59) | METAP2CDK5CDK9CAMK2ACCNB2 | |
| SCHEMBL30759515 | 0.78 | TP53 (0.47) | METAP2TNKS2CDK5CDK9CAMK2A | |
| SCHEMBL14796728 | 0.78 | KDM4E (0.59) | METAP2CDK5CDK9CAMK2ACCNB2 | |
| SCHEMBL9393238 | 0.75 | KDM4E (0.47) | METAP2CDK5CDK9CAMK2ACCNB2 | |
| SCHEMBL6827495 | 0.75 | CYP1A2 (0.62) | TNKS2TNKSHPGDSMN1; SMN2KDM4E | |
| SCHEMBL5469793 | 0.74 | HPGD (0.67) | METAP2TNKS2TNKSCDK5CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109521-A1 | PARP INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 凯复(苏州)生物医药有限公司 | 2023-06-22 | — | — | WO | disclosed |