Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 10/20 | 0.39 |
| ▸ | DRD3 | P35462 | 10/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | MET | P08581 | 5/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2567826 | 0.93 | F10 (0.42) | F10DRD2DRD3HTR1AMET | |
| SCHEMBL2571816 | 0.86 | DRD1 (0.42) | F10DRD2METALKHTR2A | |
| SCHEMBL2571246 | 0.86 | F10 (0.58) | F10DRD2DRD3HTR1AMET | |
| SCHEMBL2567220 | 0.80 | F10 (0.44) | F10ARHDAC1HDAC2 | |
| SCHEMBL2566741 | 0.79 | F10 (0.44) | F10ARHDAC1HDAC2 | |
| SCHEMBL3035739 | 0.79 | F10 (0.58) | F10DRD2METALKAR | |
| SCHEMBL2563178 | 0.79 | F10 (0.41) | F10AR | |
| SCHEMBL2569663 | 0.79 | F10 (0.41) | F10DRD2ALKAR | |
| SCHEMBL2569694 | 0.78 | F10 (0.42) | F10AR | |
| SCHEMBL2571804 | 0.78 | DRD3 (0.43) | DRD2DRD3HTR1AMETALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | claimed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | claimed |
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |