Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | TERT | O14746 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | CASP1 | P29466 | 4/20 | 0.46 |
| ▸ | CASP7 | P55210 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391481 | 1.00 | HSD17B10 (0.52) | HSD17B10ALDH1A1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL27341365 | 0.84 | KMT2A (0.58) | HSD17B10ALDH1A1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL25284840 | 0.82 | POLB (0.54) | HSD17B10ALDH1A1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL30466795 | 0.82 | POLB (0.54) | HSD17B10ALDH1A1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL31391453 | 0.79 | HRH3 (0.38) | KMT2AMEN1LMNATHRBTERT | |
| SCHEMBL25746308 | 0.79 | HRH3 (0.38) | KMT2AMEN1LMNATHRBTERT | |
| SCHEMBL31283615 | 0.77 | POLB (0.37) | HSD17B10ALDH1A1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL25746375 | 0.77 | NPC1 (0.42) | HSD17B10SMN1; SMN2LMNABLMCYP1A2 | |
| SCHEMBL31391603 | 0.75 | KDM4E (0.34) | HSD17B10ALDH1A1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL25746409 | 0.75 | KDM4E (0.34) | HSD17B10ALDH1A1KMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118507-A2 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2023-06-29 | — | — | WO | disclosed |