Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.52 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.52 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588400 | 0.98 | KMT2A (0.62) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL19582712 | 0.98 | KMT2A (0.62) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL2786767 | 0.98 | KMT2A (0.62) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL6929941 | 0.98 | KMT2A (0.62) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL3392127 | 0.98 | KMT2A (0.62) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| Bromide SCHEMBL9819629 | 0.96 | KMT2A (0.63) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL8027797 | 0.96 | KMT2A (0.60) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| Bromide SCHEMBL3703072 | 0.96 | KMT2A (0.63) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| Bromide SCHEMBL5586546 | 0.96 | KMT2A (0.63) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL9614521 | 0.96 | KMT2A (0.60) | HTTSMN1; SMN2LMNAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1750780-B1 | MEDICAL DEVICES AND METHODS OF MAKING THE SAME | BOSTON SCIENT LTD (BB) | 2007-10-03 | — | — | EP | claimed |
| EP-1750780-A1 | MEDICAL DEVICES AND METHODS OF MAKING THE SAME | Boston Scientific Limited (BB) | 2007-02-14 | — | — | EP | claimed |
| WO-2006060033-A1 | MEDICAL DEVICES AND METHODS OF MAKING THE SAME | BOSTON SCIENTIFIC LIMITED (BB) | 2006-06-08 | — | — | WO | claimed |
| US-20050261760-A1 | Medical devices and methods of making the same | BOSTON SCIENTIFIC SCIMED, INC. | 2005-11-24 | — | — | US | claimed |
| US-20040265603-A1 | Composite polyelectrolyte films for corrosion control | FSU RESEARCH FOUNDATION, INC. | 2004-12-30 | — | — | US | claimed |
| US-20040044100-A1 | Polyelectrolyte complex films for analytical and membrane separation of chiral compounds | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2004-03-04 | — | — | US | claimed |
| WO-2003014234-A1 | COMPOSITE POLYELECTROLYTE FILMS FOR CORROSION CONTROL | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2003-02-20 | — | — | WO | claimed |
| US-8048150-B2 | Endoprosthesis having a fiber meshwork disposed thereon | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2011-11-01 | — | — | US | disclosed |
| US-20070244569-A1 | Endoprosthesis having a fiber meshwork disposed thereon | BOSTON SCIENTIFIC SCIMED, INC. | 2007-10-18 | — | — | US | disclosed |
| EP-1750780-B1 | MEDICAL DEVICES AND METHODS OF MAKING THE SAME | BOSTON SCIENT LTD (BB) | 2007-10-03 | — | — | EP | disclosed |
| EP-1750780-A1 | MEDICAL DEVICES AND METHODS OF MAKING THE SAME | Boston Scientific Limited (BB) | 2007-02-14 | — | — | EP | disclosed |
| US-20070032862-A1 | Medical devices | BOSTON SCIENTIFIC SCIMED, INC. | 2007-02-08 | — | — | US | disclosed |
| WO-2006060033-A1 | MEDICAL DEVICES AND METHODS OF MAKING THE SAME | BOSTON SCIENTIFIC LIMITED (BB) | 2006-06-08 | — | — | WO | disclosed |
| US-20050261760-A1 | Medical devices and methods of making the same | BOSTON SCIENTIFIC SCIMED, INC. | 2005-11-24 | — | — | US | disclosed |
| WO-2003014234-A1 | COMPOSITE POLYELECTROLYTE FILMS FOR CORROSION CONTROL | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2003-02-20 | — | — | WO | disclosed |