SCHEMBL25751222

SCHEMBL25751222

C1=CC(c2ccc(-c3ccc(N(c4ccc(-c5cccc6ccccc56)cc4)c4ccc(-c5ccccc5)c(-c5ccc(-c6ccccc6)cc5)c4)cc3)cc2)=CCC1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
MCL1 Q07820 1/20 0.34
ACMSD Q8TDX5 1/20 0.34
PPARG P37231 8/20 0.31
PPARA Q07869 8/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
TNF P01375 1/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
PPARD Q03181 1/20 0.31
CYP1A2 P05177 1/20 0.30
ENPP3 O14638 1/20 0.30
ENPP1 P22413 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25751174 1.00 CA12 (0.36) CA12CA1CA2CA9MCL1
SCHEMBL25751218 1.00 CA12 (0.36) CA12CA1CA2CA9MCL1
SCHEMBL22809392 0.96 CA12 (0.34) CA12CA1CA2CA9MCL1
SCHEMBL25751839 0.91 MCL1 (0.34) CA12CA1CA2CA9MCL1
SCHEMBL25751197 0.90 KDM4E (0.34)
SCHEMBL24112185 0.90 MCL1 (0.31) CA12CA1CA2CA9MCL1
SCHEMBL22809345 0.90 MEN1 (0.32)
SCHEMBL22809398 0.90
SCHEMBL19597745 0.90
SCHEMBL19797561 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4198104-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2023-06-21 EP disclosed