SCHEMBL25751363

SCHEMBL25751363

CCC(C)(CC)c1ccc(-c2ccc(N3C(=O)c4ccc(Oc5ccc(C(c6ccc(Oc7ccc8c(c7)C(=O)N(C(C)(CC)CC)C8=O)cc6)(C(F)(F)F)C(F)(F)F)cc5)cc4C3=O)cc2C(F)(F)F)c(C(F)(F)F)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
NPSR1 Q6W5P4 2/20 0.37
PKM P14618 1/20 0.37
BRD4 O60885 1/20 0.35
MCHR1 Q99705 1/20 0.34
MEN1 O00255 7/20 0.33
KMT2A Q03164 7/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.32
MAPT P10636 3/20 0.32
GAA P10253 2/20 0.32
CA9 Q16790 3/20 0.31
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
LPAR1 Q92633 1/20 0.31
LPAR3 Q9UBY5 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CA2 P00918 1/20 0.31
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14045642 0.95 BRD4 (0.39) ALDH1A1NPSR1PKMBRD4MCHR1
SCHEMBL13515115 0.90 CA9 (0.36) ALDH1A1NPSR1MEN1KMT2AMAPK1
SCHEMBL25751339 0.85 NPSR1 (0.40) ALDH1A1NPSR1PKMBRD4MEN1
SCHEMBL24452956 0.85 CA9 (0.34) CA9CA12CA1CA2
SCHEMBL14444166 0.85 CA9 (0.34) CA9CA12CA1CA2
SCHEMBL14045733 0.84 CA9 (0.35) ALDH1A1NPSR1MCHR1MEN1KMT2A
SCHEMBL12994884 0.84 CA9 (0.44) ALDH1A1NPSR1MEN1KMT2AMAPK1
SCHEMBL18132899 0.84 CA9 (0.37) ALDH1A1NPSR1MEN1KMT2AMAPK1
SCHEMBL13951560 0.83 NPSR1 (0.38) ALDH1A1NPSR1PKMBRD4MCHR1
SCHEMBL12812224 0.82 BRD4 (0.48) ALDH1A1NPSR1PKMBRD4MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230205031-A1 ELECTROCHROMIC COMPOSITION, ELECTROCHROMIC LAYER AND ELECTROCHROMIC DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-29 US disclosed