Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 18/20 | 0.53 |
| ▸ | HTR2B | P41595 | 18/20 | 0.53 |
| ▸ | HTR2A | P28223 | 9/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2020049 | 1.00 | HTR2C (0.53) | HTR2CHTR2BHTR2A | |
| SCHEMBL2015254 | 0.87 | HTR2C (0.47) | HTR2CHTR2BHTR2A | |
| SCHEMBL2576950 | 0.85 | HTR2C (0.50) | HTR2CHTR2BHTR2A | |
| SCHEMBL2014029 | 0.85 | HTR2C (0.50) | HTR2CHTR2BHTR2A | |
| SCHEMBL2021572 | 0.84 | HTR2C (0.47) | HTR2CHTR2BHTR2A | |
| SCHEMBL2019564 | 0.84 | HTR2C (0.47) | HTR2CHTR2BHTR2A | |
| SCHEMBL692581 | 0.84 | HTR2C (0.47) | HTR2CHTR2BHTR2A | |
| SCHEMBL2018109 | 0.81 | HTR2C (0.62) | HTR2CHTR2BHTR2A | |
| SCHEMBL2017778 | 0.81 | HTR2C (0.58) | HTR2CHTR2BHTR2A | |
| SCHEMBL2018023 | 0.81 | HTR2C (0.44) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560973-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | Abbvie Inc. (US) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011133182-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2011-10-27 | — | — | WO | disclosed |