SCHEMBL25752468

SCHEMBL25752468

CC(C)[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@H](F)C1C

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.43
SLC28A2 O43868 1/20 0.43
SLC29A1 Q99808 1/20 0.43
SLC28A3 Q9HAS3 1/20 0.43
P2RY2 P41231 10/20 0.39
P2RY6 Q15077 7/20 0.39
TDP1 Q9NUW8 1/20 0.38
P2RY4 P51582 4/20 0.38
P2RY14 Q15391 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19397205 0.84 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL13253098 0.82 POLB (0.39) SLC28A1SLC28A2SLC29A1SLC28A3TDP1
SCHEMBL800388 0.80 SLC28A1 (0.50) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL800357 0.80 SLC28A1 (0.50) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL13274081 0.80 SLC28A1 (0.50) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL13274080 0.80 SLC28A1 (0.50) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4637211 0.80 SLC28A1 (0.50) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL14156703 0.79 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL17861840 0.79 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL17705375 0.79 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203484-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed