Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
| ▸ | CBS | P35520 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335833 | 0.87 | TSHR (0.56) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL5840370 | 0.80 | TSHR (0.43) | MGAMGAASIMGAM2TSHR | |
| Ethylene Glycol SCHEMBL9359880 | 0.79 | TSHR (0.48) | MGAMGAASIMGAM2TSHR | |
| Ethylene Glycol SCHEMBL9359829 | 0.79 | TSHR (0.48) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL3204762 | 0.78 | — | — | |
| SCHEMBL11956800 | 0.77 | TSHR (0.46) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL444220 | 0.77 | TSHR (0.46) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL692344 | 0.77 | MGAM (0.55) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL27325738 | 0.77 | — | — | |
| SCHEMBL8893700 | 0.77 | TSHR (0.46) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860561-B1 | BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS INC (US) | 2023-06-21 | — | — | EP | disclosed |