Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30895155 | 0.86 | BRD9 (0.37) | CNR2GPR139BRD9BRD4PIK3CD | |
| SCHEMBL16812315 | 0.76 | TYK2 (0.44) | CNR2GPR139BRD9AAK1P2RX7 | |
| SCHEMBL27199565 | 0.73 | TYK2 (0.35) | LMNAKMT2A | |
| SCHEMBL30895087 | 0.71 | BRD9 (0.35) | CNR2GPR139BRD9P2RX7BRD4 | |
| SCHEMBL25756040 | 0.68 | CNR2 (0.42) | CNR2P2RX7ELANEMEN1KMT2A | |
| SCHEMBL25670769 | 0.66 | CNR2 (0.42) | CNR2GPR139P2RX3P2RX7BRD4 | |
| SCHEMBL25750429 | 0.66 | ELANE (0.38) | CNR2GPR139P2RX3BRD9P2RX7 | |
| SCHEMBL25670291 | 0.66 | CNR2 (0.39) | CNR2GPR139BRD9P2RX7BRD4 | |
| SCHEMBL25756752 | 0.65 | CNR2 (0.40) | CNR2P2RX3P2RX7BRD4BACE1 | |
| SCHEMBL30895122 | 0.65 | GSK3B (0.40) | CNR2BRD9BRD4PIK3CDABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |