⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585573 | 0.80 | — | — | |
| SCHEMBL18853796 | 0.77 | — | — | |
| SCHEMBL44130 | 0.77 | — | — | |
| SCHEMBL16664765 | 0.74 | — | — | |
| SCHEMBL12522129 | 0.74 | — | — | |
| SCHEMBL7585577 | 0.74 | — | — | |
| SCHEMBL891977 | 0.74 | — | — | |
| SCHEMBL891979 | 0.74 | — | — | |
| SCHEMBL11767585 | 0.72 | — | — | |
| SCHEMBL16563081 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11759458-B2 | Indane-amines as PD-L1 antagonists | CHEMOCENTRYX, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| US-11708326-B2 | Immunomodulator compounds | CHEMOCENTRYX, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-11691985-B2 | Macrocyclic immunomodulators | CHEMOCENTRYX, INC. (US) | 2023-07-04 | — | — | US | disclosed |