⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25755541 | 0.86 | — | — | |
| SCHEMBL6438042 | 0.77 | — | — | |
| SCHEMBL4391948 | 0.77 | TSHR (0.36) | — | |
| SCHEMBL25721629 | 0.74 | TSHR (0.42) | — | |
| SCHEMBL13913111 | 0.74 | MEN1 (0.35) | — | |
| SCHEMBL12286641 | 0.73 | TSHR (0.41) | — | |
| SCHEMBL11379498 | 0.72 | — | — | |
| SCHEMBL2700439 | 0.71 | — | — | |
| SCHEMBL22609517 | 0.71 | HIF1A (0.38) | — | |
| SCHEMBL6656338 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025123007-A1 | RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS INC. (US) | 2025-06-12 | — | — | WO | disclosed |
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |