SCHEMBL25756155

SCHEMBL25756155

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4oc5cc(-n6c7ccccc7c7cc8ccccc8cc76)ccc5c4c3)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK2 O96017 1/20 0.36
PTGER4 P35408 2/20 0.34
KDM4E B2RXH2 3/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MMP12 P39900 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
NPY5R Q15761 1/20 0.31
MAPT P10636 3/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
HSD17B10 Q99714 1/20 0.31
NPC1 O15118 2/20 0.30
AHR P35869 2/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23204095 0.97 KDM4E (0.35) CHEK2PTGER4KDM4EATML3MBTL1
SCHEMBL21862705 0.96 CHEK2 (0.34) CHEK2PTGER4KDM4EATML3MBTL1
SCHEMBL23203699 0.95 CHEK2 (0.33) CHEK2PTGER4KDM4EATML3MBTL1
SCHEMBL23740447 0.94 KDM4E (0.36) PTGER4KDM4EATML3MBTL1NPY5R
SCHEMBL23203948 0.94 KDM4E (0.36) CHEK2PTGER4KDM4EATML3MBTL1
SCHEMBL24363556 0.94 CHEK2 (0.33) CHEK2PTGER4KDM4EMMP12SIRT2
SCHEMBL24152082 0.93 CHEK2 (0.39) CHEK2PTGER4KDM4EATML3MBTL1
SCHEMBL23740393 0.93 KDM4E (0.35) PTGER4KDM4EATML3MBTL1MMP12
SCHEMBL24216326 0.93 KDM4E (0.38) CHEK2PTGER4KDM4EATML3MBTL1
SCHEMBL21862710 0.93 KDM4E (0.35) CHEK2PTGER4KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217669-A1 LIGHT EMITTING DEVICE AND LIGHT EMITTING DISPLAY INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-07-06 US disclosed