⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25784935 | 1.00 | — | — | |
| SCHEMBL25785385 | 0.93 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL25756692 | 0.93 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL25032292 | 0.92 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL25756677 | 0.89 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL25784799 | 0.89 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL25756695 | 0.88 | TSHR (0.31) | — | |
| SCHEMBL25785503 | 0.88 | TSHR (0.31) | — | |
| SCHEMBL25773279 | 0.87 | — | — | |
| SCHEMBL25756106 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |