Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24863381 | 1.00 | HSD17B10 (0.48) | HSD17B10SLC6A9PIK3CDMEN1KMT2A | |
| SCHEMBL14536510 | 1.00 | HSD17B10 (0.48) | HSD17B10SLC6A9PIK3CDMEN1KMT2A | |
| SCHEMBL21964966 | 0.94 | HSD17B10 (0.44) | HSD17B10SLC6A9PIK3CDMEN1KMT2A | |
| SCHEMBL27390305 | 0.94 | HSD17B10 (0.44) | HSD17B10SLC6A9PIK3CDMEN1KMT2A | |
| SCHEMBL23435282 | 0.90 | HSD17B10 (0.41) | HSD17B10SLC6A9PIK3CDKMT2AS1PR1 | |
| SCHEMBL24090577 | 0.90 | HSD17B10 (0.41) | HSD17B10SLC6A9PIK3CDALDH1A1 | |
| SCHEMBL24090587 | 0.89 | CHRM5 (0.45) | HSD17B10SLC6A9ALDH1A1 | |
| SCHEMBL29301953 | 0.87 | HSD17B10 (0.39) | HSD17B10SLC6A9PIK3CDS1PR1ALDH1A1 | |
| SCHEMBL22434575 | 0.87 | MEN1 (0.40) | HSD17B10SLC6A9MEN1KMT2AS1PR1 | |
| SCHEMBL18377888 | 0.87 | HSD17B10 (0.39) | HSD17B10SLC6A9PIK3CDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203369-A1 | RETROGRADE NEURONAL TRACERS DETECTABLE BY FLUORESCENCE AND OTHER IMAGING METHODS | NORTHWESTERN UNIVERSITY (US) | 2023-06-29 | — | — | US | disclosed |