Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.49 |
| ▸ | ROR1 | Q01973 | 5/20 | 0.48 |
| ▸ | ABL1 | P00519 | 11/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.41 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22243490 | 0.85 | CSF1R (0.66) | CSF1RROR1ABL1 | |
| SCHEMBL29493472 | 0.85 | CSF1R (0.66) | CSF1RROR1ABL1 | |
| Hydrochloric Acid SCHEMBL29493480 | 0.76 | ABL1 (0.51) | CSF1RROR1ABL1DDR1DDR2 | |
| SCHEMBL15096062 | 0.75 | ROR1 (0.67) | CSF1RROR1ABL1KITDDR1 | |
| SCHEMBL29506341 | 0.75 | CSF1R (0.67) | CSF1RROR1ABL1 | |
| SCHEMBL24925257 | 0.74 | CSF1R (0.51) | CSF1RROR1ABL1KITDDR1 | |
| SCHEMBL24538368 | 0.73 | ABL1 (0.53) | CSF1RROR1ABL1 | |
| SCHEMBL16620724 | 0.73 | MKNK1 (0.56) | ABL1 | |
| SCHEMBL30010219 | 0.73 | CSF1R (0.72) | CSF1RROR1ABL1 | |
| SCHEMBL12652639 | 0.73 | CSF1R (0.72) | CSF1RROR1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023119334-A1 | ANTI-CANCER COMPOUND BY COMBINING PONATINIB MOLECULE WITH HDAC INHIBITOR MOLECULE USING A VARIABLE LENGTH LINKER | AMRITA VISHWA VIDYAPEETHAM (IN) | 2023-06-29 | — | — | WO | disclosed |