Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | PARP1 | P09874 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519307 | 0.72 | SRC (0.40) | SRCMAPTALDH1A1LMNAHTT | |
| SCHEMBL21246931 | 0.71 | SRC (0.37) | SRCMAPTPARP1ALDH1A1LMNA | |
| SCHEMBL20912362 | 0.71 | MAPT (0.50) | SRCMAPTPARP1ALDH1A1LMNA | |
| SCHEMBL20898582 | 0.70 | SRC (0.70) | SRCMAPTALDH1A1LMNAHTT | |
| SCHEMBL15520479 | 0.69 | MAPT (0.33) | SRCMAPTALDH1A1LMNAHTT | |
| SCHEMBL21636975 | 0.69 | PARP1 (0.41) | SRCMAPTPARP1ALDH1A1LMNA | |
| SCHEMBL22086072 | 0.69 | SRC (0.53) | SRCMAPTALDH1A1LMNAHTT | |
| SCHEMBL21246839 | 0.69 | KDM4E (0.39) | SRCMAPTALDH1A1LMNAHTT | |
| SCHEMBL21246829 | 0.68 | SMN1; SMN2 (0.39) | SRCMAPTALDH1A1LMNAHTT | |
| SCHEMBL25065700 | 0.68 | ABL1 (0.39) | SRCALDH1A1HTTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |