SCHEMBL25757623

SCHEMBL25757623

Cc1cc(C(F)(F)F)nn1CC(=O)N1CCC(c2nc(C#N)cs2)CC1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.48
CCR1 P32246 2/20 0.44
CXCR3 P49682 1/20 0.41
SPR P35270 3/20 0.40
LMNA P02545 2/20 0.39
TP53 P04637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 2/20 0.37
TSHR P16473 1/20 0.37
TLR9 Q9NR96 1/20 0.36
TLR8 Q9NR97 1/20 0.36
TLR7 Q9NYK1 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1773574 0.91 GAA (0.48) GAACCR1SPRLMNATP53
SCHEMBL1773959 0.89 GAA (0.46) GAACCR1SPRLMNATP53
SCHEMBL1228464 0.86 GAA (0.51) GAACCR1SPRLMNATP53
SCHEMBL20801744 0.86 GAA (0.51) GAACCR1SPRLMNATP53
SCHEMBL1774844 0.85 CCR1 (0.46) GAACCR1TP53L3MBTL1POLB
Hydrochloric Acid SCHEMBL1228510 0.85 GAA (0.50) GAACCR1SPRLMNATP53
SCHEMBL121172 0.85 GAA (0.50) GAACCR1SPRLMNATP53
SCHEMBL13523714 0.85 GAA (0.50) GAACCR1CXCR3SPRLMNA
SCHEMBL2509441 0.85 GAA (0.50) GAACCR1SPRLMNATP53
SCHEMBL1773839 0.85 POLB (0.44) GAACCR1CXCR3SPRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023098738-A1 COMPOUND CONTAINING OXADIAZOLE STRUCTURE AND PREPARATION METHOD THEREFOR AND USE THEREOF, AND FUNGICIDE 江苏中旗科技股份有限公司 2023-06-08 WO disclosed