SCHEMBL25757834

SCHEMBL25757834

Ic1cnc2ncnn2c1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.42
GAA P10253 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1994575 0.74 PDE10A (0.42) PDE10AGAACYP2C19
SCHEMBL23817294 0.74 PDE10A (0.42) PDE10AGAACYP2C19
SCHEMBL13510414 0.69 PDE10A (0.38) PDE10AGAACYP2C19
SCHEMBL27176974 0.67 PDE10A (0.36) PDE10ACYP2C19
SCHEMBL27177029 0.67 KDM4E (0.44) PDE10A
SCHEMBL23143459 0.67 KDR (0.54) PDE10A
SCHEMBL26419884 0.67 PDE10A (0.36) PDE10AGAACYP2C19
Ammonia Solution, Strong SCHEMBL27177005 0.66 PDE10A (0.35) PDE10ACYP2C19
SCHEMBL1585961 0.65 DYRK1A (0.47)
SCHEMBL27177097 0.65 PDE10A (0.34) PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023098880-A1 FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 上海翰森生物医药科技有限公司 2023-06-08 WO disclosed