Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266040 | 0.88 | CASR (0.53) | CASRMEN1KMT2ATDP1LMNA | |
| SCHEMBL5268907 | 0.85 | CASR (0.53) | CASRMEN1KMT2AATMPOLB | |
| SCHEMBL25759627 | 0.84 | MEN1 (0.46) | CASRMEN1KMT2AATMHTR2A | |
| SCHEMBL5269060 | 0.82 | CASR (0.56) | CASRMEN1KMT2APOLBTDP1 | |
| SCHEMBL5272819 | 0.81 | CASR (0.51) | CASRMEN1KMT2AHTR2ASLC6A4 | |
| SCHEMBL5268791 | 0.80 | CASR (0.53) | CASRMEN1KMT2ATDP1LMNA | |
| SCHEMBL5273132 | 0.77 | CASR (0.57) | CASRMEN1KMT2ATDP1LMNA | |
| SCHEMBL5273084 | 0.77 | CASR (0.57) | CASRMEN1KMT2APOLBTDP1 | |
| SCHEMBL5267036 | 0.74 | CASR (0.61) | CASRMEN1KMT2ASLC6A4TDP1 | |
| SCHEMBL5273390 | 0.74 | TDP1 (0.45) | CASRMEN1KMT2AHTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098880-A1 | FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2023-06-08 | — | — | WO | disclosed |