Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465320 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6064245 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6064107 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL13063465 | 0.80 | KDM4E (0.37) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6064133 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL19086058 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL203038 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL16195634 | 0.77 | KDM4E (0.36) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL14117842 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL13346726 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028279-A1 | GATE INSULATOR LAYER FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |