Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | TTK | P33981 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.38 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3702290 | 0.86 | PIK3CG (0.45) | SMARCA2SMARCA4LRRK2PIK3CDPIK3CA | |
| SCHEMBL29824713 | 0.78 | LRRK2 (0.41) | SMARCA2SMARCA4LRRK2PIK3CDPIK3CA | |
| SCHEMBL23630930 | 0.78 | SMARCA2 (0.43) | SMARCA2SMARCA4LRRK2PIK3CDPIK3CA | |
| SCHEMBL3702267 | 0.78 | LRRK2 (0.42) | SMARCA2SMARCA4LRRK2PIK3CDPIK3CA | |
| SCHEMBL20150492 | 0.78 | LRRK2 (0.42) | LRRK2PIK3CDPIK3CAPIK3CGTTK | |
| SCHEMBL23421146 | 0.73 | LRRK2 (0.49) | LRRK2PIK3CDPIK3CATTK | |
| SCHEMBL2745470 | 0.73 | QPCT (0.46) | PIK3CDPIK3CAPIK3CGTTKAURKA | |
| SCHEMBL22047858 | 0.73 | MAPT (0.58) | LRRK2PIK3CDPIK3CAPIK3CGTTK | |
| SCHEMBL19171737 | 0.72 | FGFR1 (0.40) | SMARCA2SMARCA4LRRK2PIK3CDPIK3CA | |
| SCHEMBL29757761 | 0.72 | CHEK1 (0.55) | CCNA2CDK2CHEK1CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116888-A1 | FIVE- AND SIX-MEMBERED COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 杭州多域生物技术有限公司 | 2023-06-29 | — | — | WO | disclosed |