Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.67 |
| ▸ | GSPT1 | P15170 | 5/20 | 0.67 |
| ▸ | IKZF3 | Q9UKT9 | 5/20 | 0.67 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.48 |
| ▸ | WIZ | O95785 | 1/20 | 0.47 |
| ▸ | IKZF1 | Q13422 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413572 | 0.89 | CRBN (0.78) | CRBNGSPT1IKZF3DDB1CYP2C19 | |
| SCHEMBL30751909 | 0.89 | CRBN (0.62) | CRBNGSPT1IKZF3DDB1CYP2C19 | |
| SCHEMBL62069 | 0.88 | CRBN (0.63) | CRBNGSPT1IKZF3DDB1CYP2C19 | |
| SCHEMBL12802526 | 0.87 | CRBN (0.62) | CRBNGSPT1IKZF3DDB1CYP2C19 | |
| SCHEMBL61093 | 0.84 | CRBN (0.60) | CRBNGSPT1IKZF3DDB1CYP2C19 | |
| SCHEMBL63298 | 0.84 | CRBN (0.59) | CRBNGSPT1IKZF3DDB1CYP2C19 | |
| SCHEMBL31338135 | 0.83 | IKZF2 (0.56) | CRBNGSPT1IKZF3DDB1CYP2C19 | |
| SCHEMBL24113908 | 0.83 | CRBN (0.66) | CRBNGSPT1IKZF3DDB1CYP2C19 | |
| SCHEMBL1413509 | 0.83 | CRBN (0.77) | CRBNGSPT1IKZF3DDB1CYP2C19 | |
| SCHEMBL22685614 | 0.83 | CRBN (0.76) | CRBNGSPT1IKZF3DDB1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116835-A1 | MULTI-PROTEIN DEGRADATION AGENT HAVING IMIDE SKELETON | 苏州开拓药业股份有限公司 | 2023-06-29 | — | — | WO | disclosed |