Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 14/20 | 0.58 |
| ▸ | ELOC | Q15369 | 2/20 | 0.57 |
| ▸ | ELOB | Q15370 | 2/20 | 0.57 |
| ▸ | ACACB | O00763 | 5/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23205254 | 0.93 | VHL (0.52) | VHLELOCELOBSOS1 | |
| SCHEMBL25898817 | 0.92 | VHL (0.51) | VHLELOCELOBSOS1 | |
| SCHEMBL25901663 | 0.89 | VHL (0.48) | VHLELOCELOBSOS1 | |
| SCHEMBL25894289 | 0.89 | VHL (0.48) | VHLELOCELOBSOS1 | |
| SCHEMBL25769161 | 0.87 | VHL (0.43) | VHLELOCELOBACACB | |
| SCHEMBL25900160 | 0.87 | VHL (0.48) | VHLELOCELOBACACB | |
| SCHEMBL25893485 | 0.87 | VHL (0.46) | VHLELOCELOBACACBSOS1 | |
| SCHEMBL21697292 | 0.86 | VHL (0.76) | VHLELOCELOB | |
| SCHEMBL25769085 | 0.86 | VHL (0.76) | VHLELOCELOB | |
| SCHEMBL25771807 | 0.85 | VHL (0.76) | VHLELOCELOBSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203030-A1 | COMPOUNDS AND METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS | ARVINAS OPERATIONS, INC. | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203030-A1 | COMPOUNDS AND METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS | VHL, MDM2, XIAP | VHL 1/4885ELOC 203/4885ELOB 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.