Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695092 | 0.83 | KDM4E (0.52) | KDM4EPKMGPR119USP30MEN1 | |
| SCHEMBL10128539 | 0.80 | USP2 (0.40) | GPR119MAPK1NAMPTRORCNR1H2 | |
| SCHEMBL2292608 | 0.77 | USP2 (0.52) | GPR119MAPK1NAMPTMEN1KMT2A | |
| SCHEMBL26427290 | 0.76 | KDM4E (0.46) | KDM4EPKMGPR119NAMPTUSP30 | |
| SCHEMBL27688065 | 0.75 | MAPK1 (0.45) | KDM4EPKMGPR119MAPK1ALDH1A1 | |
| SCHEMBL27952715 | 0.75 | SMARCA2 (0.48) | KDM4EPKMGPR119USP30MEN1 | |
| SCHEMBL25717306 | 0.75 | KDM4E (0.50) | KDM4EPKMGPR119ALDH1A1USP30 | |
| SCHEMBL23830485 | 0.74 | KDM4E (0.48) | KDM4EPKMGPR119MAPK1NAMPT | |
| SCHEMBL24718695 | 0.74 | USP30 (0.47) | KDM4EPKMGPR119USP30MEN1 | |
| SCHEMBL25628792 | 0.74 | KDM4E (0.52) | KDM4EPKMGPR119ALDH1A1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116774-A1 | COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE | 赛诺哈勃药业（成都）有限公司 | 2023-06-29 | — | — | WO | disclosed |