SCHEMBL25775892 — predicted protein targets

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	TNKS	O95271	4/20	0.40

▸	TNKS2	Q9H2K2	4/20	0.40

▸	P2RY14	Q15391	7/20	0.39

▸	SYK	P43405	1/20	0.38

▸	KCNH2	Q12809	3/20	0.38

▸	PARP1	P09874	2/20	0.38

▸	TGFBR1	P36897	1/20	0.38

▸	ACVR1	Q04771	1/20	0.38

▸	JAK2	O60674	1/20	0.36

▸	TLR9	Q9NR96	2/20	0.36

▸	TLR8	Q9NR97	2/20	0.36

▸	TLR7	Q9NYK1	2/20	0.36

▸	ADRB3	P13945	2/20	0.36

▸	ADRA2B	P18089	2/20	0.36

▸	DRD1	P21728	2/20	0.36

▸	DRD5	P21918	2/20	0.36

▸	ADRA1B	P35368	2/20	0.36

▸	TMEM97	Q5BJF2	2/20	0.36

▸	SIGMAR1	Q99720	2/20	0.36

▸	RET	P07949	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25775967	0.81	ACVR1 (0.46)	KCNH2TGFBR1ACVR1CDK4CDK6
SCHEMBL25777158	0.76	JAK2 (0.34)	TNKSTNKS2P2RY14KCNH2PARP1
SCHEMBL25775957	0.74	RPS6KA3 (0.43)	TNKSTNKS2PARP1TGFBR1ACVR1
SCHEMBL25775893	0.74	TNKS (0.47)	TNKSTNKS2P2RY14SYKKCNH2
SCHEMBL22051240	0.72	HTR2C (0.50)	TNKSTNKS2P2RY14KCNH2PARP1
SCHEMBL25236499	0.69	EGFR (0.42)	TNKSTNKS2SYKKCNH2PARP1
SCHEMBL30478867	0.69	EGFR (0.42)	TNKSTNKS2SYKKCNH2PARP1
SCHEMBL25785822	0.69	KCNH2 (0.37)	KCNH2PARP1
SCHEMBL25775952	0.66	GRM4 (0.36)	KCNH2
SCHEMBL29363744	0.62	MAPK14 (0.43)	TNKSTNKS2P2RY14SYKPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023116779-A1	DIALKYNE COMPOUND AND USE THEREOF	上海艾力斯医药科技股份有限公司	2023-06-29	—	—	WO	disclosed